MAST1

Across TCGA cell cohorts, MAST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,675 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAST1-associated GO terms across cancer lineages are Locomotory exploration behavior, Positive regulation of double-strand break repair, and Regulation of protein localization to centrosome. Each is linked with MAST1 in more than 12 cancer types. Because this analysis shows association rather than direction, both MAST1-to-partner and partner-to-MAST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Locomotory exploration behavior grouped by MAST1-low versus MAST1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAST1→partner) and Y-score (partner→MAST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Locomotory exploration behavior →	+0.264	+1.414	.005	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.072	+0.796	.004	.002	3	13
URINARY_TRACT	Regulation of protein localization to centrosome →	+0.101	+1.132	.008	.005	3	12
BONE	Negative regulation of gene expression, epigenetic →	+0.086	+1.997	<.001	.001	2	13
BONE	Positive regulation of DNA repair →	+0.063	+1.592	<.001	<.001	3	12
STOMACH	Sodium ion homeostasis →	-0.228	-1.022	<.001	.009	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,675 associations by consensus.

Locomotory exploration behavior by MAST1 expression — OESOPHAGUS

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