MAS1

Across TCGA cell cohorts, MAS1 RNA expression is significantly associated with the drug of many other genes, with 38 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MAS1-associated genes across cancer lineages are Wee1 Inhibitor, FS112, and N25720-51-A1. Each is linked with MAS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAS1-to-partner and partner-to-MAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wee1 Inhibitor grouped by MAS1-low versus MAS1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAS1→partner) and Y-score (partner→MAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Wee1 Inhibitor →	-0.656	-0.005	.037	.015	3	2
UPPER_AERODIGESTIVE_TRACT	FS112 →	-0.675	-0.004	.011	.033	3	2
UPPER_AERODIGESTIVE_TRACT	N25720-51-A1 →	-0.617	-0.005	.024	.015	3	2
UPPER_AERODIGESTIVE_TRACT	AZ6102 →	-0.472	-0.004	.033	.024	3	2
UPPER_AERODIGESTIVE_TRACT	TL-2-105 →	-0.303	-0.006	.035	.039	3	2
BLOOD_Lymphoma	Vinblastine →	-0.594	-0.026	.016	.029	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Wee1 Inhibitor by MAS1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →