MAS1

Across TCGA pan-cancer cohorts, MAS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MAS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where MAS1 RNA is repressed in tumor relative to normal tissue. In most cancer types MAS1 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

UCEC, COAD, and BRCA are the cancer types where MAS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	−0.580	<.001	8	view →
COAD	All	All	+0.006	<.001	7	view →
BRCA	All	All	−0.033	<.001	4	view →
THCA	Female	All	−0.019	<.001	4	view →
KIRP	Male	All	−0.018	.013	4	view →
KIRC	Male	All	−0.014	.016	4	view →
KICH	All	II,III,IV	−0.007	.025	3	view →
READ	Male	All	+0.030	.033	2	view →
HNSC	All	III,IV	+0.023	.016	1	view →
LUAD	Female	All	−0.019	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MAS1–UCEC

Open the UCEC breakdown →