MAPT-IT1

Across TCGA patient cohorts, MAPT-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,511 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAPT-IT1-associated proteins across cancer lineages are VEZF1, THEMIS2, and TLR2. Each is linked with MAPT-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAPT-IT1-to-partner and partner-to-MAPT-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPT-IT1 versus VEZF1 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPT-IT1→partner) and Y-score (partner→MAPT-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VEZF1 →	+0.436	+0.573	<.001	<.001	3	5
BRCA	THEMIS2 →	-0.523	-0.764	<.001	<.001	3	4
GBM	TLR2 →	-0.506	-0.941	<.001	<.001	3	4
BRCA	TNKS1BP1_S1652 →	-0.744	-0.497	<.001	<.001	3	4
LSCC	TXNDC5 →	-0.486	-0.183	<.001	<.001	3	4
BRCA	UNC13D →	-0.460	-0.580	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,511 associations by consensus.

MAPT-IT1 vs VEZF1 — BRCA

Explore this scatter interactively →