MAPKAPK5

Across TCGA patient cohorts, MAPKAPK5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,801 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAPKAPK5-associated genes across cancer lineages are CCNT1, GATC, and SPAG1. Each is linked with MAPKAPK5 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAPKAPK5-to-partner and partner-to-MAPKAPK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAPKAPK5 versus CCNT1 in OV, with a Pearson correlation of 0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPKAPK5→partner) and Y-score (partner→MAPKAPK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCNT1 →	+1.085	+1.015	.003	.002	3	3
LSCC	GATC →	+0.390	+0.269	<.001	<.001	3	3
OV	SPAG1 →	-1.625	-1.015	.001	.002	3	2
OV	TOR1AIP2 →	+1.245	+1.015	.007	.002	3	2
OV	C12orf73 →	+1.064	+1.015	<.001	.002	3	2
LSCC	ZCCHC8 →	+0.303	+0.238	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,801 associations by consensus.

MAPKAPK5 vs CCNT1 — OV

Explore this scatter interactively →