MAPK9

Across TCGA cell cohorts, MAPK9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,276 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAPK9-associated GO terms across cancer lineages are Regulation of cell cycle checkpoint, Positive regulation of organelle assembly, and Phosphatidylinositol biosynthetic process. Each is linked with MAPK9 in more than 12 cancer types. Because this analysis shows association rather than direction, both MAPK9-to-partner and partner-to-MAPK9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle checkpoint grouped by MAPK9-low versus MAPK9-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK9→partner) and Y-score (partner→MAPK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of cell cycle checkpoint →	+0.092	+0.800	<.001	.001	3	13
BLOOD_Myeloma	Positive regulation of organelle assembly →	+0.062	+0.767	.006	.003	3	13
LARGE_INTESTINE	Phosphatidylinositol biosynthetic process →	+0.061	+0.829	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.072	+1.164	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Negative regulation of hippo signaling →	+0.107	+0.908	<.001	.004	3	12
BONE	Post-Golgi vesicle-mediated transport →	+0.072	+1.020	.003	.005	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,276 associations by consensus.

Regulation of cell cycle checkpoint by MAPK9 expression — OVARY

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