MAPK13

Across TCGA patient cohorts, MAPK13 mutation is significantly associated with the RNA expression of many other genes, with 249 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAPK13-associated genes across cancer lineages are KIAA1143P2, MIR3925, and RN7SL677P. Each is linked with MAPK13 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAPK13-to-partner and partner-to-MAPK13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIAA1143P2 grouped by MAPK13-low versus MAPK13-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK13→partner) and Y-score (partner→MAPK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	KIAA1143P2 →	+0.110	+4.812	<.001	.006	3	2
CESC	MIR3925 →	+0.318	+5.144	<.001	.003	3	2
HNSC	RN7SL677P →	+0.157	+5.182	<.001	.007	3	2
BLCA	RNU7-126P →	+0.837	+7.640	<.001	.009	3	2
BLCA	RNU6-622P →	+0.363	+7.640	<.001	.009	3	2
UCEC	RNA5SP204 →	+0.473	+2.888	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 249 associations by consensus.

KIAA1143P2 by MAPK13 expression — CESC

Explore this box plot interactively →