MAPK13

Across TCGA pan-cancer cohorts, MAPK13 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MAPK13 data layer compared with 4 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MAPK13 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MAPK13 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

KIRC, KIRP, and SKCM are the cancer types where MAPK13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.801	0.577	<.001	76	view →
KIRP	DFS	Median	IV	0.038	0.525	.019	30	view →
SKCM	DFS	Median	All	0.248	0.160	.002	26	view →
SCLC	OS	Quartile	All	0.574	0.262	.007	20	view →
COAD	DFS	Quartile	II,III,IV	0.689	0.818	.018	20	view →
LUAD	OS	Median	II,III,IV	0.570	0.355	.026	18	view →
READ	DFS	Median	All	0.865	0.770	.025	12	view →
LUSC	OS	Median	II,III,IV	0.801	0.676	.013	11	view →
LIHC	OS	Quartile	All	0.601	0.765	.012	10	view →
PCPG	DFS	Tertile	All	0.965	0.815	.015	8	view →
KICH	DFS	Median	II,III,IV	0.576	0.882	.016	7	view →
MESO	OS	Median	All	0.294	0.674	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MAPK13–KIRC (OS)

Open the KIRC breakdown →