MAPK13

Across TCGA cell cohorts, MAPK13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,389 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MAPK13-associated GO terms across cancer lineages are Cellular response to anisomycin, Cellular response to molecule of fungal origin, and Response to sorbitol. Each is linked with MAPK13 in more than 12 cancer types. Because this analysis shows association rather than direction, both MAPK13-to-partner and partner-to-MAPK13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to anisomycin grouped by MAPK13-low versus MAPK13-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK13→partner) and Y-score (partner→MAPK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cellular response to anisomycin →	+0.190	+2.253	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Cellular response to molecule of fungal origin →	+1.649	+2.307	<.001	<.001	3	11
URINARY_TRACT	Response to sorbitol →	+0.193	+3.587	.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of heart rate by cardiac conduction →	+0.231	+2.574	<.001	.003	3	11
LUNG_NSCLC_LUSC	Serotonin secretion →	+1.552	+2.307	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Response to molecule of fungal origin →	+1.649	+2.307	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,389 associations by consensus.

Cellular response to anisomycin by MAPK13 expression — LUNG_SCLC

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