MAPK13

Across TCGA cell cohorts, MAPK13 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAPK13-associated genes across cancer lineages are SYT10, MYOT, and CNGB3. Each is linked with MAPK13 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAPK13-to-partner and partner-to-MAPK13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYT10 grouped by MAPK13-low versus MAPK13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAPK13→partner) and Y-score (partner→MAPK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SYT10 →	+0.199	+3.196	<.001	.007	3	1
LARGE_INTESTINE	MYOT →	+0.111	+3.845	.001	.003	3	1
LARGE_INTESTINE	CNGB3 →	+0.214	+3.643	<.001	.005	3	1
LARGE_INTESTINE	UTF1 →	+0.018	+3.632	<.001	.003	3	1
LARGE_INTESTINE	SERTM1 →	+0.015	+3.554	.001	.007	3	1
LARGE_INTESTINE	ELOA3DP →	+0.036	+3.688	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

SYT10 by MAPK13 expression — LARGE_INTESTINE

Explore this box plot interactively →