MAP7D3

Across TCGA patient cohorts, MAP7D3 mutation is significantly associated with the RNA expression of many other genes, with 1,361 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP7D3-associated genes across cancer lineages are OR11L1, LINC02002, and CXXC1. Each is linked with MAP7D3 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP7D3-to-partner and partner-to-MAP7D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11L1 grouped by MAP7D3-low versus MAP7D3-high in ACC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP7D3→partner) and Y-score (partner→MAP7D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	OR11L1 →	+0.049	+5.662	<.001	.002	3	2
ACC	LINC02002 →	+0.036	+5.662	<.001	.002	3	2
UCEC	CXXC1 →	+0.307	+1.999	.001	.002	3	2
UCEC	MFSD12 →	+0.353	+1.884	.001	<.001	3	2
UCEC	CIAO2B →	+0.306	+1.917	.001	<.001	3	2
UCEC	COQ4 →	+0.264	+1.365	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,361 associations by consensus.

OR11L1 by MAP7D3 expression — ACC

Explore this box plot interactively →