MAP6

Across TCGA patient cohorts, MAP6 protein abundance is significantly associated with the RNA expression of many other genes, with 9,648 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP6-associated genes across cancer lineages are SHE, DES, and SFRP1. Each is linked with MAP6 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP6-to-partner and partner-to-MAP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP6 versus SHE in CCRCC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP6→partner) and Y-score (partner→MAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SHE →	+0.838	+0.413	<.001	.002	3	6
COAD	DES →	+2.408	+0.479	<.001	<.001	3	6
UCEC	SFRP1 →	+1.649	+0.811	<.001	<.001	3	6
PDAC	ADH1B →	+1.484	+0.591	<.001	<.001	3	6
GBM	JPH4 →	+1.524	+0.840	<.001	<.001	3	6
HNSC	LDB3 →	+0.852	+0.503	.009	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,648 associations by consensus.

MAP6 vs SHE — CCRCC

Explore this scatter interactively →