MAP3K8

Across TCGA patient cohorts, MAP3K8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,367 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP3K8-associated proteins across cancer lineages are NCF1, FERMT3, and FGD3. Each is linked with MAP3K8 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAP3K8-to-partner and partner-to-MAP3K8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K8 versus NCF1 in GBM, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K8→partner) and Y-score (partner→MAP3K8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCF1 →	+0.946	+1.384	<.001	<.001	3	7
GBM	FERMT3 →	+0.809	+1.460	<.001	<.001	3	7
GBM	FGD3 →	+0.602	+1.452	<.001	<.001	3	7
GBM	MAP3K8_S141 →	+0.842	+1.393	<.001	<.001	3	7
GBM	THEMIS2_T593 →	+0.697	+1.181	<.001	<.001	3	7
COAD	TRPV2 →	+0.430	+0.651	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,367 associations by consensus.

MAP3K8 vs NCF1 — GBM

Explore this scatter interactively →