MAP3K8

Across TCGA patient cohorts, MAP3K8 protein abundance is significantly associated with the RNA expression of many other genes, with 16,261 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP3K8-associated genes across cancer lineages are ARHGAP9, FAM78A, and CD84. Each is linked with MAP3K8 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP3K8-to-partner and partner-to-MAP3K8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K8 versus ARHGAP9 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K8→partner) and Y-score (partner→MAP3K8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ARHGAP9 →	+0.997	+0.390	<.001	.001	3	5
HNSC	FAM78A →	+0.964	+0.443	<.001	<.001	3	5
HNSC	CD84 →	+0.809	+0.419	.003	.001	2	6
HNSC	IL12RB1 →	+0.529	+0.231	.005	.006	3	5
HNSC	RASAL3 →	+0.939	+0.425	<.001	<.001	3	4
BRCA	CD4 →	+0.792	+0.353	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,261 associations by consensus.

MAP3K8 vs ARHGAP9 — HNSC

Explore this scatter interactively →