MAP3K7CL

Across TCGA patient cohorts, MAP3K7CL mutation is significantly associated with the RNA expression of many other genes, with 1,658 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP3K7CL-associated genes across cancer lineages are KRTAP22-1, RNU6-1040P, and MIR378E. Each is linked with MAP3K7CL in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP3K7CL-to-partner and partner-to-MAP3K7CL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP22-1 grouped by MAP3K7CL-low versus MAP3K7CL-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K7CL→partner) and Y-score (partner→MAP3K7CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KRTAP22-1 →	+0.254	+7.930	<.001	.008	3	2
LUAD	RNU6-1040P →	+0.497	+7.930	<.001	.008	3	2
UCEC	MIR378E →	+0.243	+3.132	<.001	.005	3	2
UCEC	SNRPGP17 →	+0.266	+2.200	<.001	.001	3	1
UCEC	RPL23AP90 →	+0.332	+1.954	<.001	.004	3	1
UCEC	DCP1A →	+0.597	+3.345	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,658 associations by consensus.

KRTAP22-1 by MAP3K7CL expression — LUAD

Explore this box plot interactively →