MAP3K21

Across TCGA cell cohorts, MAP3K21 protein abundance is significantly associated with the RNA expression of many other genes, with 2,092 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP3K21-associated genes across cancer lineages are ERI2, KAT8, and PDPK1. Each is linked with MAP3K21 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAP3K21-to-partner and partner-to-MAP3K21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K21 versus ERI2 in LIVER, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K21→partner) and Y-score (partner→MAP3K21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ERI2 →	+0.920	+1.232	.009	.005	3	5
LIVER	KAT8 →	+0.806	+0.957	.002	.005	3	5
LUNG_SCLC	PDPK1 →	+0.630	+0.992	.004	.005	3	5
BLOOD_Leukemia	S1PR3 →	-1.803	-0.551	.002	.009	3	5
LUNG_NSCLC_LUSC	MMD →	+2.031	+1.413	.001	.001	3	4
LUNG_NSCLC_LUSC	KIF13B →	+1.476	+1.436	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,092 associations by consensus.

MAP3K21 vs ERI2 — LIVER

Explore this scatter interactively →