MAP3K15

Across TCGA cell cohorts, MAP3K15 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,963 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MAP3K15-associated GO terms across cancer lineages are Mucus secretion, IMP biosynthetic process, and Cellular response to 2,3,7,8-tetrachlorodibenzodioxine. Each is linked with MAP3K15 in more than 10 cancer types. Because this analysis shows association rather than direction, both MAP3K15-to-partner and partner-to-MAP3K15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mucus secretion grouped by MAP3K15-low versus MAP3K15-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K15→partner) and Y-score (partner→MAP3K15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mucus secretion →	-0.688	-0.892	.007	.004	3	10
BONE	IMP biosynthetic process →	+0.174	+0.752	.009	.003	1	11
OVARY	Cellular response to 2,3,7,8-tetrachlorodibenzodioxine →	-0.941	-1.114	<.001	<.001	3	9
OVARY	Positive regulation of sodium ion transmembrane transport →	-0.214	-0.789	.002	.005	3	9
LUNG_NSCLC_LUAD	Cell-cell adhesion mediated by cadherin →	-0.111	-0.880	.002	<.001	3	8
LUNG_SCLC	Positive regulation of transcription by RNA polymerase I →	+0.072	+1.082	.009	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,963 associations by consensus.

Mucus secretion by MAP3K15 expression — OVARY

Explore this box plot interactively →