MAP3K14

Across TCGA patient cohorts, MAP3K14 protein abundance is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP3K14-associated genes across cancer lineages are TIMP3, SNX25, and FAM122A. Each is linked with MAP3K14 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP3K14-to-partner and partner-to-MAP3K14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K14 versus TIMP3 in GBM, with a Pearson correlation of -0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K14→partner) and Y-score (partner→MAP3K14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TIMP3 →	-1.616	-1.079	.001	.003	3	1
GBM	SNX25 →	-0.503	-0.950	.005	.001	3	1
GBM	FAM122A →	-0.693	-1.116	.009	.001	3	1
GBM	RPL21P1 →	-0.946	-1.116	.007	.001	3	1
GBM	LINC01946 →	-1.756	-1.116	.002	.001	3	1
GBM	RBM26-AS1 →	-0.623	-1.079	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MAP3K14 vs TIMP3 — GBM

Explore this scatter interactively →