long intergenic non-protein coding RNA 1946Genealiases: []
Q-omics provides the consensus-scored LINC01946 profile across patient tissues and cancer cell-line models. LINC01946 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, LINC01946 is differentially expressed in 3, with the highest sampling consensus in BRCA. Additionally, LINC01946 RNA expression shows 6,627 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ACC, BRCA, and STAD as cancer lineages where LINC01946 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01946 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01946 survival associations across molecular data types. LINC01946 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01946 RNA expression–survival associations across cancer types. High LINC01946 expression shows unfavorable associations in ACC, THCA, KIRC, MESO, UVM and KIRP. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for LINC01946 RNA expression.
This table summarizes LINC01946 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01946. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01946 shows higher tumor expression in BRCA, KIRC and LIHC. The BRCA box plot shows higher LINC01946 RNA expression in tumor versus normal tissue (log2 FC = +0.129, t-test p = .022).
This table shows molecular features associated with LINC01946 in patient tissues and cancer cell lines. In patient samples, LINC01946 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
