Across TCGA patient cohorts, MAP1LC3C mutation is significantly associated with the RNA expression of many other genes, with 534 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP1LC3C-associated genes across cancer lineages are RNA5SP95, FGF7P5, and RNU6-518P. Each is linked with MAP1LC3C in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP1LC3C-to-partner and partner-to-MAP1LC3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3C→partner) and Y-score (partner→MAP1LC3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP95 →	+0.375	+5.685	<.001	.003	3	2
LUSC	FGF7P5 →	+0.198	+6.102	<.001	.001	3	2
LUSC	RNU6-518P →	+0.414	+6.102	<.001	.001	3	2
BLCA	H3P35 →	+0.276	+5.588	<.001	.004	3	2
BLCA	MIR615 →	+0.800	+5.411	<.001	.005	3	2
BRCA	MIR8062 →	+0.582	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 534 associations by consensus.

Exploration

MAP1LC3C survival (RNA) · tumor vs normal (RNA) · all MAP1LC3C data types