Across TCGA patient cohorts, MAP1LC3C mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible MAP1LC3C-associated genes across cancer lineages are MPP, Preadipocytes, and CD4+ Tcm. Each is linked with MAP1LC3C in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP1LC3C-to-partner and partner-to-MAP1LC3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3C→partner) and Y-score (partner→MAP1LC3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MPP →	+0.013	+3.694	.002	.027	3	2
LUAD	Preadipocytes →	+0.033	+2.239	.001	.028	3	1
HNSC	CD4+ Tcm →	+0.013	+5.468	<.001	.043	3	1
LUSC	CMP →	+0.048	+3.315	<.001	.040	3	1
LUSC	GMP →	+0.043	+4.849	.018	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

MAP1LC3C survival (RNA) · tumor vs normal (RNA) · all MAP1LC3C data types