MANEA-DT

Across TCGA patient cohorts, MANEA-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 11,089 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MANEA-DT-associated proteins across cancer lineages are PSIP1, OPLAH_T151, and CDC40. Each is linked with MANEA-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both MANEA-DT-to-partner and partner-to-MANEA-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MANEA-DT versus PSIP1 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MANEA-DT→partner) and Y-score (partner→MANEA-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PSIP1 →	+0.553	+0.624	<.001	<.001	3	4
LUAD	OPLAH_T151 →	-1.031	-0.262	<.001	.006	3	4
LSCC	CDC40 →	+0.231	+0.363	<.001	.004	3	4
HNSC	GABPA →	+0.207	+0.592	<.001	<.001	3	4
GBM	GATAD2B →	+0.357	+0.557	<.001	.002	3	4
LUAD	DSP_S2024 →	-1.098	-0.291	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,089 associations by consensus.

MANEA-DT vs PSIP1 — HNSC

Explore this scatter interactively →