MAN2B1

Across TCGA patient cohorts, MAN2B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,107 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAN2B1-associated proteins across cancer lineages are DOCK8, GMIP, and HCLS1. Each is linked with MAN2B1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAN2B1-to-partner and partner-to-MAN2B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAN2B1 versus DOCK8 in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2B1→partner) and Y-score (partner→MAN2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DOCK8 →	+0.566	+0.669	<.001	<.001	3	8
CCRCC	GMIP →	+0.372	+0.498	<.001	<.001	3	8
GBM	HCLS1 →	+0.797	+0.662	<.001	<.001	3	8
GBM	LCP1 →	+0.702	+0.610	<.001	<.001	3	8
GBM	LPXN →	+0.669	+0.558	<.001	<.001	3	8
GBM	PTPN6 →	+0.618	+0.652	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,107 associations by consensus.

MAN2B1 vs DOCK8 — GBM

Explore this scatter interactively →