MAN2B1

Across TCGA patient cohorts, MAN2B1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,443 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAN2B1-associated genes across cancer lineages are LY9, MRPL35, and PARP15. Each is linked with MAN2B1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAN2B1-to-partner and partner-to-MAN2B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAN2B1 versus LY9 in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2B1→partner) and Y-score (partner→MAN2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LY9 →	+0.716	+0.256	.001	<.001	3	5
LSCC	MRPL35 →	-0.480	-0.243	<.001	<.001	3	5
HNSC	PARP15 →	+0.941	+0.199	<.001	.003	3	5
LSCC	COPDA1 →	+0.901	+0.306	<.001	<.001	3	5
LSCC	ARHGAP15 →	+0.693	+0.268	.001	.002	3	5
GBM	HLA-DPB1 →	+0.735	+0.223	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,443 associations by consensus.

MAN2B1 vs LY9 — HNSC

Explore this scatter interactively →