MAN2B1

Across TCGA cell cohorts, MAN2B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,448 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAN2B1-associated GO terms across cancer lineages are Negative regulation of respiratory burst involved in inflammatory response, Negative regulation of respiratory burst, and Carbohydrate catabolic process. Each is linked with MAN2B1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAN2B1-to-partner and partner-to-MAN2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of respiratory burst involved in inflammatory response grouped by MAN2B1-low versus MAN2B1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2B1→partner) and Y-score (partner→MAN2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of respiratory burst involved in inflammatory response →	+0.148	+0.990	<.001	<.001	3	12
BLOOD_Lymphoma	Negative regulation of respiratory burst →	+0.148	+0.990	<.001	<.001	3	12
SOFT_TISSUE	Carbohydrate catabolic process →	+0.063	+0.701	<.001	.001	3	11
BONE	Mannose metabolic process →	+0.175	+1.237	<.001	.002	3	11
CNS	Response to type III interferon →	+0.187	+0.711	<.001	<.001	3	10
SOFT_TISSUE	Glycolipid catabolic process →	+0.155	+0.860	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,448 associations by consensus.

Negative regulation of respiratory burst involved in inflammatory response by MAN2B1 expression — BLOOD_Lymphoma

Explore this box plot interactively →