MAN2A1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAN2A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,847 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAN2A1-associated proteins across cancer lineages are AP3S1, NUP205, and RBM26. Each is linked with MAN2A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAN2A1-to-partner and partner-to-MAN2A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAN2A1 versus AP3S1 in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2A1→partner) and Y-score (partner→MAN2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCAP3S1 →+0.198+0.369<.001<.00136
BRCANUP205 →-0.267-0.799<.001<.00135
GBMRBM26 →-0.244-0.746<.001<.00135
LUADPJA2_S253 →+0.384+0.412.002.00835
GBMADNP →-0.402-0.897<.001<.00135
LSCCMGAT1 →+0.294+0.285<.001.00534
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,847 associations by consensus.

MAN2A1 vs AP3S1 — LSCC

Per-sample scatter of MAN2A1 vs AP3S1 in LSCC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration