MAN2A1-DT

Across TCGA patient cohorts, MAN2A1-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,104 significant associations in total. LGG shows the largest number of these associations.

The most reproducible MAN2A1-DT-associated GO terms across cancer lineages are mRNA 3'-splice site recognition, Proton motive force-driven ATP synthesis, and Ribosomal small subunit export from nucleus. Each is linked with MAN2A1-DT in more than 15 cancer types. Because this analysis shows association rather than direction, both MAN2A1-DT-to-partner and partner-to-MAN2A1-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 3'-splice site recognition grouped by MAN2A1-DT-low versus MAN2A1-DT-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2A1-DT→partner) and Y-score (partner→MAN2A1-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	mRNA 3'-splice site recognition →	+0.052	+1.116	<.001	<.001	3	16
UVM	Proton motive force-driven ATP synthesis →	+0.042	+0.478	<.001	<.001	3	13
UVM	Ribosomal small subunit export from nucleus →	+0.047	+0.330	.002	.002	3	12
GBM	Protein deglycosylation →	+0.044	+0.473	<.001	<.001	3	12
UVM	Vesicle coating →	+0.044	+0.418	<.001	<.001	3	12
UVM	Mitochondrial respiratory chain complex assembly →	+0.031	+0.362	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,104 associations by consensus.

mRNA 3'-splice site recognition by MAN2A1-DT expression — THYM

Explore this box plot interactively →