MAN1A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAN1A2 mutation is significantly associated with the RNA expression of many other genes, with 5,004 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAN1A2-associated genes across cancer lineages are MIR4774, CCL5, and RN7SL248P. Each is linked with MAN1A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAN1A2-to-partner and partner-to-MAN1A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN1A2→partner) and Y-score (partner→MAN1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READMIR4774 →+0.841+6.257<.001.00132
UCECCCL5 →+0.808+2.906.005.00132
UCECRN7SL248P →+0.053+2.967<.001.00132
UCECMIR6780B →+0.191+1.830.002.00932
LIHCPRAMEF25 →+0.014+5.902<.001.00132
LIHCNANOGP10 →+0.060+4.758<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,004 associations by consensus.

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