MAMSTR

Across TCGA patient cohorts, MAMSTR mutation is significantly associated with the RNA expression of many other genes, with 1,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAMSTR-associated genes across cancer lineages are RNA5SP421, RNU4-58P, and SLC44A3P1. Each is linked with MAMSTR in more than 1 cancer types. Because this analysis shows association rather than direction, both MAMSTR-to-partner and partner-to-MAMSTR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP421 grouped by MAMSTR-low versus MAMSTR-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAMSTR→partner) and Y-score (partner→MAMSTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP421 →	+0.551	+2.411	.007	.002	3	2
SKCM	RNU4-58P →	+0.367	+4.970	<.001	.005	3	2
SKCM	SLC44A3P1 →	+0.025	+4.771	<.001	.006	3	2
UCEC	LINC01607 →	-0.848	-3.438	<.001	.005	3	1
UCEC	ZNHIT3 →	+0.473	+2.721	.005	.003	3	1
UCEC	PRAG1 →	+0.815	+2.617	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,023 associations by consensus.

RNA5SP421 by MAMSTR expression — UCEC

Explore this box plot interactively →