MALL

Across TCGA cell cohorts, MALL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,144 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MALL-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Negative regulation of actin filament depolymerization, and Regulation of actin polymerization or depolymerization. Each is linked with MALL in more than 11 cancer types. Because this analysis shows association rather than direction, both MALL-to-partner and partner-to-MALL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of actin filament polymerization grouped by MALL-low versus MALL-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MALL→partner) and Y-score (partner→MALL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of actin filament polymerization →	+0.151	+3.715	.001	.004	2	12
LUNG_NSCLC_LUAD	Negative regulation of actin filament depolymerization →	+0.126	+1.893	<.001	.001	3	10
OESOPHAGUS	Regulation of actin polymerization or depolymerization →	+0.097	+3.217	<.001	<.001	3	10
KIDNEY	Axon ensheathment →	+0.074	+3.272	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Actin filament capping →	+0.158	+2.423	<.001	<.001	3	9
KIDNEY	Myelination →	+0.080	+2.830	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,144 associations by consensus.

Negative regulation of actin filament polymerization by MALL expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →