MALL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MALL mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MALL-associated genes across cancer lineages are TECRL. Each is linked with MALL in more than 1 cancer types. Because this analysis shows association rather than direction, both MALL-to-partner and partner-to-MALL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TECRL grouped by MALL-low versus MALL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MALL→partner) and Y-score (partner→MALL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETECRL →+0.026+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TECRL by MALL expression — LARGE_INTESTINE

Box plot of TECRL in MALL-low vs MALL-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration