MAILR

Across TCGA patient cohorts, MAILR RNA expression is significantly associated with the protein abundance of many other proteins, with 13,211 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAILR-associated proteins across cancer lineages are RPL3, RPL7A, and RPS6. Each is linked with MAILR in more than 5 cancer types. Because this analysis shows association rather than direction, both MAILR-to-partner and partner-to-MAILR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAILR versus RPL3 in GBM, with a Pearson correlation of -0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAILR→partner) and Y-score (partner→MAILR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL3 →	-0.387	-0.618	<.001	<.001	3	6
GBM	RPL7A →	-0.307	-0.408	<.001	.006	3	5
GBM	RPS6 →	-0.527	-0.587	<.001	<.001	3	5
GBM	RPS8 →	-0.340	-0.529	.001	<.001	3	5
BRCA	HDGFL3 →	+0.659	+0.383	<.001	<.001	3	5
GBM	RPL7 →	-0.379	-0.468	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,211 associations by consensus.

MAILR vs RPL3 — GBM

Explore this scatter interactively →