MAGOHB

Across TCGA patient cohorts, MAGOHB mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGOHB-associated genes across cancer lineages are OR7E159P, PRR27, and SMIM11P1. Each is linked with MAGOHB in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGOHB-to-partner and partner-to-MAGOHB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E159P grouped by MAGOHB-low versus MAGOHB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGOHB→partner) and Y-score (partner→MAGOHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR7E159P →	+0.208	+3.567	.008	.005	3	2
UCEC	PRR27 →	+0.499	+3.604	<.001	.009	3	1
UCEC	SMIM11P1 →	+0.422	+3.800	<.001	.001	3	1
UCEC	RNU4-58P →	+0.374	+3.718	<.001	.004	3	1
UCEC	RNU6-271P →	+0.495	+4.437	<.001	.001	3	1
UCEC	C7orf66 →	+0.377	+3.086	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

OR7E159P by MAGOHB expression — UCEC

Explore this box plot interactively →