MAGI1

Across TCGA cell cohorts, MAGI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,598 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MAGI1-associated GO terms across cancer lineages are Heterochromatin formation, Negative regulation of gene expression, epigenetic, and Regulation of double-strand break repair via homologous recombination. Each is linked with MAGI1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAGI1-to-partner and partner-to-MAGI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by MAGI1-low versus MAGI1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGI1→partner) and Y-score (partner→MAGI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heterochromatin formation →	+0.097	+1.295	<.001	<.001	3	12
BONE	Negative regulation of gene expression, epigenetic →	+0.096	+1.170	.001	.001	3	12
BONE	Regulation of double-strand break repair via homologous recombination →	+0.141	+1.315	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.082	+1.203	<.001	<.001	3	11
SOFT_TISSUE	Regulation of RNA stability →	+0.072	+1.234	<.001	.001	3	11
BONE	Positive regulation of DNA recombination →	+0.144	+1.371	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,598 associations by consensus.

Heterochromatin formation by MAGI1 expression — BONE

Explore this box plot interactively →