MAGED4

Across TCGA cell cohorts, MAGED4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,809 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAGED4-associated GO terms across cancer lineages are Nucleoside triphosphate biosynthetic process, Regulation of termination of RNA polymerase II transcription, and Regulation of termination of DNA-templated transcription. Each is linked with MAGED4 in more than 12 cancer types. Because this analysis shows association rather than direction, both MAGED4-to-partner and partner-to-MAGED4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate biosynthetic process grouped by MAGED4-low versus MAGED4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGED4→partner) and Y-score (partner→MAGED4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.097	+1.507	<.001	<.001	3	13
LUNG_SCLC	Regulation of termination of RNA polymerase II transcription →	+0.093	+1.905	.001	<.001	3	12
LUNG_SCLC	Regulation of termination of DNA-templated transcription →	+0.093	+1.905	.001	<.001	3	12
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.110	+1.507	<.001	<.001	3	12
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.065	+2.107	<.001	<.001	3	12
OESOPHAGUS	DNA-templated transcription initiation →	+0.079	+1.671	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,809 associations by consensus.

Nucleoside triphosphate biosynthetic process by MAGED4 expression — OESOPHAGUS

Explore this box plot interactively →