MAGEB4

Across TCGA patient cohorts, MAGEB4 mutation is significantly associated with the RNA expression of many other genes, with 5,038 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEB4-associated genes across cancer lineages are RN7SL697P, TK1, and FCER1A. Each is linked with MAGEB4 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEB4-to-partner and partner-to-MAGEB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL697P grouped by MAGEB4-low versus MAGEB4-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB4→partner) and Y-score (partner→MAGEB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SL697P →	+0.138	+5.063	.003	.001	3	3
UCEC	TK1 →	+0.530	+2.021	<.001	<.001	3	3
LUAD	FCER1A →	-1.525	-3.988	<.001	<.001	3	2
UCEC	MEX3D →	+0.730	+1.805	<.001	<.001	3	2
UCEC	ODF3L2 →	+0.264	+1.398	.003	.004	3	2
UCEC	TRAIP →	+0.460	+2.269	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,038 associations by consensus.

RN7SL697P by MAGEB4 expression — HNSC

Explore this box plot interactively →