MAGEB4

Across TCGA pan-cancer cohorts, MAGEB4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MAGEB4’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MAGEB4 RNA is repressed in tumor relative to normal tissue. In most cancer types MAGEB4 is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.

BRCA and COAD are the cancer types where MAGEB4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAGEB4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.214	<.001	6	view →
COAD	All	II,III,IV	−0.005	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MAGEB4–BRCA

Open the BRCA breakdown →