MAGEB18

Across TCGA patient cohorts, MAGEB18 mutation is significantly associated with the RNA expression of many other genes, with 1,888 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEB18-associated genes across cancer lineages are ANKRD20A6P, NAALADL2-AS1, and HMGN1P15. Each is linked with MAGEB18 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEB18-to-partner and partner-to-MAGEB18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD20A6P grouped by MAGEB18-low versus MAGEB18-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB18→partner) and Y-score (partner→MAGEB18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANKRD20A6P →	+0.153	+8.055	<.001	.007	3	2
HNSC	NAALADL2-AS1 →	+0.054	+3.310	.002	.009	3	2
HNSC	HMGN1P15 →	+0.195	+3.140	.004	.006	3	2
UCEC	CXCL9 →	+2.047	+3.906	<.001	<.001	3	2
UCEC	MYO19 →	+0.471	+2.287	.001	.005	3	2
LUAD	RMDN2 →	-0.675	-2.700	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,888 associations by consensus.

ANKRD20A6P by MAGEB18 expression — BRCA

Explore this box plot interactively →