Across TCGA patient cohorts, MAGEA1 protein abundance is significantly associated with the RNA expression of many other genes, with 609 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MAGEA1-associated genes across cancer lineages are POTEE, TOMM40P2, and BCRP9. Each is linked with MAGEA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA1-to-partner and partner-to-MAGEA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA1→partner) and Y-score (partner→MAGEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POTEE →	+2.342	+2.079	<.001	<.001	3	2
LSCC	TOMM40P2 →	+1.371	+1.212	<.001	.001	3	2
HNSC	BCRP9 →	+1.509	+2.075	<.001	<.001	3	2
LSCC	TOMM40P1 →	+1.298	+1.343	<.001	<.001	3	2
LSCC	ARL4AP1 →	-0.686	-0.906	.003	.001	3	1
LSCC	BARX1 →	+1.640	+0.872	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 609 associations by consensus.

Exploration

MAGEA1 survival (RNA) · tumor vs normal (RNA) · all MAGEA1 data types