Across TCGA patient cohorts, MAGEA1 mutation is significantly associated with the RNA expression of many other genes, with 2,971 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA1-associated genes across cancer lineages are NDUFA5P2, RN7SL478P, and AKR1A1. Each is linked with MAGEA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA1-to-partner and partner-to-MAGEA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA1→partner) and Y-score (partner→MAGEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NDUFA5P2 →	+0.735	+4.321	<.001	.002	3	2
COAD	RN7SL478P →	+0.457	+4.730	<.001	.001	3	2
SKCM	AKR1A1 →	+0.443	+3.334	.002	.005	3	2
SKCM	HECTD3 →	+0.545	+2.328	<.001	.003	3	2
UCEC	ANKMY1 →	-0.461	-3.563	.006	.002	3	2
COAD	MIR552 →	+1.107	+4.666	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,971 associations by consensus.

Exploration

MAGEA1 survival (RNA) · tumor vs normal (RNA) · all MAGEA1 data types