Across TCGA patient cohorts, MAGEA1 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA1-associated genes across cancer lineages are INPP4B, eIF4E, and p21. Each is linked with MAGEA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA1-to-partner and partner-to-MAGEA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA1→partner) and Y-score (partner→MAGEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.258	-1.893	.047	.016	3	2
UCEC	eIF4E →	+0.198	+3.183	.019	.009	3	1
UCEC	p21 →	+0.172	+1.906	.026	.016	3	1
UCEC	PCNA →	+0.280	+3.700	.001	.001	3	1
UCEC	Annexin-1 →	+0.469	+2.341	.027	.019	3	1
UCEC	VHL →	-1.141	-1.807	<.001	.025	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

MAGEA1 survival (RNA) · tumor vs normal (RNA) · all MAGEA1 data types