Across TCGA cell cohorts, MAGEA1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MAGEA1-associated genes across cancer lineages are DCD, SMIM28, and ZNF831. Each is linked with MAGEA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA1-to-partner and partner-to-MAGEA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA1→partner) and Y-score (partner→MAGEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DCD →	+0.092	+4.562	<.001	<.001	3	1
SKIN	SMIM28 →	+0.016	+4.437	<.001	.004	3	1
CNS	ZNF831 →	+0.051	+3.662	<.001	.001	3	1
CNS	GPHA2 →	+0.326	+3.000	<.001	.007	3	1
CNS	IL22RA2 →	+0.302	+3.000	<.001	.006	3	1
CNS	KLK15 →	+0.144	+3.906	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

MAGEA1 survival (RNA) · tumor vs normal (RNA) · all MAGEA1 data types