MADD-AS1

Across TCGA patient cohorts, MADD-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,714 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MADD-AS1-associated proteins across cancer lineages are RERE_S656, SART3, and HNRNPUL1. Each is linked with MADD-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MADD-AS1-to-partner and partner-to-MADD-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MADD-AS1 versus RERE_S656 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MADD-AS1→partner) and Y-score (partner→MADD-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RERE_S656 →	+0.386	+0.286	.001	.004	3	4
UCEC	SART3 →	+0.175	+0.579	.003	.002	3	4
GBM	HNRNPUL1 →	+0.321	+0.381	<.001	<.001	3	4
GBM	CCAR1 →	+0.199	+0.365	.002	.007	3	4
GBM	CPSF7 →	+0.265	+0.325	<.001	<.001	3	4
HNSC	PDLIM1 →	-0.452	-0.766	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,714 associations by consensus.

MADD-AS1 vs RERE_S656 — BRCA

Explore this scatter interactively →