MAD2L1BP

Across TCGA patient cohorts, MAD2L1BP protein abundance is significantly associated with the RNA expression of many other genes, with 13,149 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAD2L1BP-associated genes across cancer lineages are SNX25, RNF8, and CDC25A. Each is linked with MAD2L1BP in more than 2 cancer types. Because this analysis shows association rather than direction, both MAD2L1BP-to-partner and partner-to-MAD2L1BP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAD2L1BP versus SNX25 in LUAD, with a Pearson correlation of -0.20.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAD2L1BP→partner) and Y-score (partner→MAD2L1BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SNX25 →	-0.492	-0.166	.003	.006	3	3
LSCC	RNF8 →	+0.550	+0.350	<.001	<.001	3	3
UCEC	CDC25A →	+0.919	+0.213	<.001	.002	3	3
LSCC	LILRA1 →	-0.339	-0.289	.001	.001	3	2
LSCC	SIAE →	-0.429	-0.268	<.001	.001	3	2
LUAD	COQ5 →	+0.352	+0.333	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,149 associations by consensus.

MAD2L1BP vs SNX25 — LUAD

Explore this scatter interactively →