MAD2L1BP

Across TCGA cell cohorts, MAD2L1BP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,722 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MAD2L1BP-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, DNA-templated transcription initiation, and Regulation of transcription initiation by RNA polymerase II. Each is linked with MAD2L1BP in more than 10 cancer types. Because this analysis shows association rather than direction, both MAD2L1BP-to-partner and partner-to-MAD2L1BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by MAD2L1BP-low versus MAD2L1BP-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAD2L1BP→partner) and Y-score (partner→MAD2L1BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein peptidyl-prolyl isomerization →	+0.142	+0.736	<.001	<.001	3	11
BLOOD_Leukemia	DNA-templated transcription initiation →	+0.051	+0.556	<.001	<.001	3	11
BREAST	Regulation of transcription initiation by RNA polymerase II →	+0.062	+0.875	<.001	<.001	3	10
OVARY	Trophectodermal cell differentiation →	+0.140	+0.453	<.001	.003	3	10
BLOOD_Lymphoma	Protein-DNA complex assembly →	+0.050	+0.734	<.001	<.001	3	10
LIVER	Negative regulation of RNA export from nucleus →	+0.167	+0.702	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,722 associations by consensus.

Protein peptidyl-prolyl isomerization by MAD2L1BP expression — LIVER

Explore this box plot interactively →