MACROH2A2

Across TCGA patient cohorts, MACROH2A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,147 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MACROH2A2-associated proteins across cancer lineages are MACROH2A2_S129, ZMYM2, and MACROH2A2_S175. Each is linked with MACROH2A2 in more than 8 cancer types. Because this analysis shows association rather than direction, both MACROH2A2-to-partner and partner-to-MACROH2A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACROH2A2 versus MACROH2A2_S129 in BRCA, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROH2A2→partner) and Y-score (partner→MACROH2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MACROH2A2_S129 →	+0.946	+1.252	<.001	<.001	3	9
LSCC	ZMYM2 →	+0.570	+0.774	<.001	<.001	3	6
GBM	MACROH2A2_S175 →	+1.213	+2.020	.008	.004	3	5
LUAD	TYMP_T154 →	-0.655	-0.494	.001	.006	3	4
LSCC	SP110_S380 →	-0.615	-0.698	<.001	<.001	3	4
OV	SPIN1 →	+0.366	+0.578	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,147 associations by consensus.

MACROH2A2 vs MACROH2A2_S129 — BRCA

Explore this scatter interactively →