MACROH2A1

Across TCGA patient cohorts, MACROH2A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,047 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MACROH2A1-associated proteins across cancer lineages are KDM3B, MACROH2A1_T129, and YTHDC2. Each is linked with MACROH2A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MACROH2A1-to-partner and partner-to-MACROH2A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACROH2A1 versus KDM3B in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROH2A1→partner) and Y-score (partner→MACROH2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KDM3B →	+0.389	+0.412	<.001	<.001	3	6
PDAC	MACROH2A1_T129 →	+0.506	+0.305	.004	.001	3	6
OV	YTHDC2 →	+0.309	+0.646	.001	<.001	3	6
GBM	CHAF1B →	+0.805	+0.426	<.001	<.001	3	6
GBM	MCM3 →	+0.789	+0.366	<.001	.001	3	5
GBM	MCM7 →	+0.864	+0.401	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,047 associations by consensus.

MACROH2A1 vs KDM3B — GBM

Explore this scatter interactively →