MACROD2-IT1

Across TCGA patient cohorts, MACROD2-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,245 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MACROD2-IT1-associated proteins across cancer lineages are MACROD2, PLEKHA6_S777, and RALGAPB. Each is linked with MACROD2-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MACROD2-IT1-to-partner and partner-to-MACROD2-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACROD2-IT1 versus MACROD2 in GBM, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROD2-IT1→partner) and Y-score (partner→MACROD2-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MACROD2 →	+0.973	+0.882	<.001	<.001	3	5
PDAC	PLEKHA6_S777 →	+0.839	+0.412	<.001	<.001	3	4
LSCC	RALGAPB →	+0.271	+0.606	<.001	<.001	3	4
HNSC	OCRL →	+0.207	+0.521	.006	.007	3	3
PDAC	PIK3CG_S974 →	-0.460	-0.327	.002	.004	3	3
GBM	PLCB1 →	+0.470	+0.672	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,245 associations by consensus.

MACROD2-IT1 vs MACROD2 — GBM

Explore this scatter interactively →