MACROD2-IT1

Across TCGA patient cohorts, MACROD2-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,916 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MACROD2-IT1-associated GO terms across cancer lineages are Nucleotide-excision repair, Glycerophospholipid biosynthetic process, and tRNA metabolic process. Each is linked with MACROD2-IT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both MACROD2-IT1-to-partner and partner-to-MACROD2-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-excision repair grouped by MACROD2-IT1-low versus MACROD2-IT1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROD2-IT1→partner) and Y-score (partner→MACROD2-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nucleotide-excision repair →	+0.048	+0.100	<.001	<.001	2	14
STAD	Glycerophospholipid biosynthetic process →	+0.044	+0.068	<.001	<.001	3	12
STAD	tRNA metabolic process →	+0.053	+0.089	<.001	<.001	3	12
ESCA	tRNA processing →	+0.050	+0.071	<.001	.001	3	12
STAD	Phospholipid biosynthetic process →	+0.046	+0.071	<.001	<.001	3	12
STAD	Regulation of microtubule-based process →	+0.039	+0.097	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,916 associations by consensus.

Nucleotide-excision repair by MACROD2-IT1 expression — ESCA

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