MACROD2-AS1

Across TCGA patient cohorts, MACROD2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,642 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MACROD2-AS1-associated GO terms across cancer lineages are Protein localization to mitochondrion, Positive regulation of DNA repair, and Positive regulation of double-strand break repair. Each is linked with MACROD2-AS1 in more than 18 cancer types. Because this analysis shows association rather than direction, both MACROD2-AS1-to-partner and partner-to-MACROD2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to mitochondrion grouped by MACROD2-AS1-low versus MACROD2-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROD2-AS1→partner) and Y-score (partner→MACROD2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to mitochondrion →	+0.048	+0.123	<.001	<.001	3	19
STAD	Positive regulation of DNA repair →	+0.047	+0.134	<.001	<.001	3	18
STAD	Positive regulation of double-strand break repair →	+0.051	+0.138	<.001	<.001	3	18
STAD	Regulation of binding →	+0.052	+0.149	<.001	<.001	3	18
STAD	RNA 3'-end processing →	+0.053	+0.130	<.001	<.001	3	17
STAD	Regulation of telomere maintenance →	+0.057	+0.140	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,642 associations by consensus.

Protein localization to mitochondrion by MACROD2-AS1 expression — STAD

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